The UMD-DMD France mutations database
Distribution of mutations at the exonic level

This function analyzes the distribution of small rearrangements at the exonic level.

Only mutations found in probands are analyzed. For each exon, the expected value is calculated according to the exon's size, the exon's composition (mutability of each codon) and the number of mutations.

Exon	Expected mutations	Observed mutations	Missense mutations	Other mutations	Statistical significance
1	4	1	0	1	<0.2
2	7	3	1	2	<0.2
3	10	12	0	12	<0.9
4	8	7	0	7	<0.9
5	10	10	2	8	<0.9
6	20	32	0	32	<0.01
7	13	20	0	20	<0.1
8	21	20	0	20	<0.9
9	14	7	0	7	<0.1
10	21	29	0	29	<0.1
11	21	22	2	20	<0.9
12	17	19	0	19	<0.9
13	13	11	0	11	<0.9
14	12	20	0	20	<0.02
15	12	19	2	17	<0.1
16	20	24	0	24	<0.5
17	20	18	0	18	<0.9
18	14	25	1	24	<0.01
19	10	22	1	21	<0.001
20	28	33	3	30	<0.5
21	20	26	0	26	<0.2
22	17	20	2	18	<0.5
23	24	39	0	39	<0.01
24	13	17	0	17	<0.3
25	18	8	1	7	<0.02
26	20	18	0	18	<0.9
27	21	19	0	19	<0.9
28	15	6	0	6	<0.02
29	17	3	1	2	<0.001
30	18	16	0	16	<0.9
31	13	4	1	3	<0.02
32	20	25	0	25	<0.3
33	18	21	0	21	<0.5
34	20	28	0	28	<0.1
35	20	30	0	30	<0.05
36	15	19	0	19	<0.5
37	19	17	0	17	<0.9
38	14	12	1	11	<0.9
39	16	22	0	22	<0.2
40	18	30	0	30	<0.01
41	20	25	0	25	<0.5
42	22	10	0	10	<0.02
43	20	18	0	18	<0.9
44	17	28	0	28	<0.01
45	20	12	1	11	<0.1
46	17	10	0	10	<0.1
47	17	12	2	10	<0.3
48	21	15	0	15	<0.3
49	11	2	0	2	<0.01
50	12	6	0	6	<0.1
51	25	12	0	12	<0.01
52	14	20	0	20	<0.2
53	24	21	0	21	<0.9
54	18	13	0	13	<0.3
55	21	22	0	22	<0.9
56	20	12	1	11	<0.1
57	17	9	0	9	<0.1
58	14	17	2	15	<0.5
59	29	28	0	28	<0.9
60	16	14	0	14	<0.9
61	9	13	0	13	<0.2
62	7	10	0	10	<0.2
63	8	5	0	5	<0.5
64	8	9	0	9	<0.9
65	23	9	0	9	<0.01
66	9	15	0	15	<0.1
67	17	7	0	7	<0.02
68	19	14	1	13	<0.3
69	13	19	5	14	<0.1
70	15	76	0	76	<0.001
71	4	0	0	0	<0.05
72	7	1	0	1	<0.05
73	7	0	0	0	<0.01
74	18	13	0	13	<0.3
75	26	10	0	10	<0.01
76	13	2	0	2	<0.01
77	11	0	0	0	<0.01
78	3	0	0	0	<0.1
79	2	0	0	0	<0.2