For each amino acids are displayed the number of residues in the TREAT_DMD protein and its frequency; the expected number of mutations if events were randomly distributed and the observed number of mutations affecting these residues. A click on the an amino acid gives access to a detailed table of substitutions and other mutations.
A click on the "Detailed view of mutations at the AA level" will display a summary table of all events.
| Amino Acid | Number in the protein | Expected number of mutations | Observed number of mutations | ||
|---|---|---|---|---|---|
| Ala | 213 | (5.78 %) | 71.9 | 17 | (1.37 %) |
| Arg | 198 | (5.37 %) | 66.8 | 266 | (21.38 %) |
| Asn | 165 | (4.48 %) | 55.7 | 25 | (2.01 %) |
| Asp | 193 | (5.23 %) | 65.1 | 23 | (1.85 %) |
| Cys | 36 | (0.98 %) | 12.1 | 13 | (1.05 %) |
| Gln | 307 | (8.33 %) | 103.6 | 259 | (20.82 %) |
| Glu | 388 | (10.52 %) | 130.9 | 132 | (10.61 %) |
| Gly | 112 | (3.04 %) | 37.8 | 29 | (2.33 %) |
| His | 88 | (2.39 %) | 29.7 | 9 | (0.72 %) |
| Ile | 171 | (4.64 %) | 57.7 | 21 | (1.69 %) |
| Leu | 456 | (12.37 %) | 153.9 | 94 | (7.56 %) |
| Lys | 293 | (7.95 %) | 98.9 | 97 | (7.8 %) |
| Met | 80 | (2.17 %) | 27 | 7 | (0.56 %) |
| Phe | 81 | (2.2 %) | 27.3 | 11 | (0.88 %) |
| Pro | 131 | (3.55 %) | 44.2 | 18 | (1.45 %) |
| Ser | 243 | (6.59 %) | 82 | 72 | (5.79 %) |
| Stop | 1 | (0.03 %) | 0.3 | 0 | (0 %) |
| Thr | 200 | (5.42 %) | 67.5 | 19 | (1.53 %) |
| Trp | 72 | (1.95 %) | 24.3 | 71 | (5.71 %) |
| Tyr | 62 | (1.68 %) | 20.9 | 37 | (2.97 %) |
| Val | 197 | (5.34 %) | 66.5 | 23 | (1.85 %) |