Changelog

Version 3.0 - May 24, 2013

  • Implementation of GC donor matrices
  • Integration of the "help to interprete" tool
  • Creation of a webservice
  • New web interface
  • Graphical representations were replaced by new dynamics graphs
  • Integration of NNSplice from Reese & al.
  • Update of Ensembl human dataset - Version 70, February 2013 (Hg19)
  • New optional fields added in the submission form: Gene status and Transcript status
  • Hugo Gene Nomenclature Committee data integration
  • Visualisation of the wild type position of branch point in "Analyse mutation(s)" added
  • Bugs fixed

Version 2.4.1 - Octover 13, 2010

Version 2.4 - November 12, 2008

  • Integration of MaxEnt programs from G. Yeo and CB Burge
  • New matrices added for detecting splicing impact of variants in position +3
  • Support for indels and duplications in the "Quick mutation" system added
  • Search database with Consensus CDS
  • New optional fields added in the submission form: Exon number and Intron number
  • Use of separate 5' and 3' intronic sequence lengths
  • SNPs highlighted directly into the sequences in "Analyze mutation(s)" and "Multiple Transcript Analysis"
  • Minor presentation changes
  • Bugs fixed

Version 2.3 - May 27, 2008

  • EIE and IIE matrices from Zhang et al. added
  • "Multiple Transcript Analysis" added. A new analysis type allowing the user to analyze mutants from different transcripts in a single process.
  • "RefSeq Peptide ID" field added for querying the database
  • "Quick mutation" system extended to mutants, "Branch point sequence" and "splice site" analysis
  • SNP search and impact analysis extended to mutants
  • SNPs highlighted directly into the sequence in "Analyze a sequence", "Branch point sequence" and "splice site analysis"
  • Line delimiting AGEZ added in branch point analysis
  • Splicing Sequences Finder (SSF) name changed for Human Splicing Finder (HSF)
  • Minor presentation changes
  • Bugs fixed

Version 2.2.1 - January 22, 2008

  • Correction of bugs in display for the "Analyze mutation(s)" section

Version 2.2 - December 14, 2007

  • "Analyze a mutation" and "Analyze mutation(s)" sections are now merged into one section: "Analyze mutation(s)"
  • Users can choose their thresholds for ESE Finder matrices
  • New matrix from ESE Finder 3 for SF2/ASF (IgM-BRCA1) added
  • In batch mutant analysis, extension to intronic substitutions
  • Deletions and insertions are now allowed in batch mutant analysis and mutant comparison for both exonic and intronic mutations
  • In batch mutant analysis, duplications and inversions are now allowed (exonic mutations only)
  • Integration of data from the SNPs databases available on Ensembl
  • Integration of Exonic Splicing Regulatory sequences from Goren et al.
  • "Quick mutation" system added, allowing the user to quickly create a mutant from the currently sequence displayed in the "Analyze a sequence" section. Only substitutions, deletions and insertions are permitted for now.
  • New field for querying the database (Ensembl gene ID) added
  • Bug fixed

Version 2.1 - July 5, 2007

  • New matrices integration for Tra2, 9G8 and hnRNP A1

Version 2.0 - June 16, 2007

  • Integration of Ensembl Human dataset - Version 44, April 2007 (Hg18)
  • New web interface
  • Separate analysis for branch points
  • Separate analysis for potential splicing donors and acceptors
  • Integration of batch mutant analysis (substitutions only)

Version 1.1 - January 25, 2006

  • First public release of Splicing Sequences Finder